Evaluation of saturation index of lymphoma patients
Gazi Universitesi Eczacilik Fakultesi Dergisi, cilt.14, sa.1, ss.5-10, 1997 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 14 Sayı: 1
- Basım Tarihi: 1997
- Dergi Adı: Gazi Universitesi Eczacilik Fakultesi Dergisi
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.5-10
- Anahtar Kelimeler: Lymphoma patients, Oleic acid, Saturation index, Stearic acid, Tumor markers
- Lokman Hekim Üniversitesi Adresli: Evet
Özet
The saturation index of erythrocyte membrane lipids (stearate to oleate ratio) was determined by gas-liquid chromatography in lymphoma patients (before and after treatment) and in 30 healthy controls. The ratio of stearic acid/oleic acid (18:0/18:1) in the heathy control group was significantly higher (p<0.001) than the pre-treated lymphoma patients and the same significance existed between the pre-and post treated patients (p<0.001). Although the reason for the persistent changes in stearic acid/oleic acid ratio are not known, and assumed that the factors secreted by tumor makes the cell membrane unstable, such a clear test could have major implications for cancer screening and for monitoring of recurrence and response to treatment.