Therapeutic Potential of alpha- and beta-Pinene: A Miracle Gift of Nature
BIOMOLECULES, cilt.9, sa.11, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 9 Sayı: 11
- Basım Tarihi: 2019
- Doi Numarası: 10.3390/biom9110738
- Dergi Adı: BIOMOLECULES
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: alpha-pinene, beta-pinene, pharmacological activities, cytotoxicity, bioavailability, clinical studies, ESSENTIAL OIL COMPONENTS, NF-KAPPA-B, SALVIA-LAVANDULAEFOLIA, CHEMICAL-COMPOSITION, ANTIINFLAMMATORY ACTIVITY, ANTIMICROBIAL EVALUATION, PHARMACOLOGICAL-ACTIVITY, ANTIOXIDANT ACTIVITIES, BIOLOGICAL-ACTIVITIES, MAJOR CONSTITUENT
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Lokman Hekim Üniversitesi Adresli: Hayır
Özet
alpha- and beta-pinene are well-known representatives of the monoterpenes group, and are found in many plants' essential oils. A wide range of pharmacological activities have been reported, including antibiotic resistance modulation, anticoagulant, antitumor, antimicrobial, antimalarial, antioxidant, anti-inflammatory, anti-Leishmania, and analgesic effects. This article aims to summarize the most prominent effects of alpha- and beta-pinene, namely their cytogenetic, gastroprotective, anxiolytic, cytoprotective, anticonvulsant, and neuroprotective effects, as well as their effects against H2O2-stimulated oxidative stress, pancreatitis, stress-stimulated hyperthermia, and pulpal pain. Finally, we will also discuss the bioavailability, administration, as well as their biological activity and clinical applications.