Intrathecal gadolinium-enhanced MR cisternography in the evaluation of clinically suspected cerebrospinal fluid rhinorrhea in humans: Early experience

Jinkins J. R., Rudwan M., Krumina G., TALI E. T.

Radiology, vol.222, no.2, pp.555-559, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 222 Issue: 2
  • Publication Date: 2002
  • Doi Number: 10.1148/radiol.2222010249
  • Journal Name: Radiology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.555-559
  • Keywords: cerebrospinal fluid, leakage, cisternography, MR, fistula, cerebrospinal, magnetic resonance (MR), contrast media, METRIZAMIDE CT-CISTERNOGRAPHY, HIGH-RESOLUTION CT, CSF FISTULAS, GADOPENTETATE DIMEGLUMINE, SUBARACHNOID SPACE, CONTRAST-MEDIA, LOCALIZATION, MYELOGRAPHY, DIAGNOSIS, INJECTION
  • Lokman Hekim University Affiliated: No

Abstract

In this prospective multicenter study, the authors evaluated the utility of magnetic resonance (MR) cisternography after intrathecal administration of gadopentetate dimeglumine in 15 patients clinically suspected of having cerebrospinal fluid (CSF) rhinorrhea. By means of lumbar puncture, a single dose of 0.5 mL of gadopentetate dimeglumine was injected into the lumbar subarachnoid space. Thirteen patients showed leakage of contrast material through the cribriform plate into the ethmoid or sphenoid air cells. No leakage was observed in two patients. The study results show the relative safety and feasibility of low-dose gadolinium-enhanced MR cisternography in confirming the presence and determining the focus of active CSF leaks.