Nocardiosis in a teaching hospital in the Central Anatolia region of Turkey: treatment and outcome

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YILDIZ O., ALP E., TOKGOZ B., TUCER B., AYGEN B., SUMERKAN B., ...More

CLINICAL MICROBIOLOGY AND INFECTION, vol.11, no.6, pp.495-499, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 6
  • Publication Date: 2005
  • Doi Number: 10.1111/j.1469-0691.2005.01145.x
  • Journal Name: CLINICAL MICROBIOLOGY AND INFECTION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.495-499
  • Keywords: antimicrobial susceptibility, cerebral infection, Nocardia spp., predisposing factors, pulmonary infection, Turkey, LUNG-TRANSPLANT RECIPIENTS, INFECTION
  • Lokman Hekim University Affiliated: No

Abstract

Predisposing factors, antimicrobial susceptibility patterns, treatment and outcome were analysed for nine consecutive patients with nocardiosis. Predisposing factors were identified in six (67%) of the nine patients. Clinical syndromes of nocardial infection were pulmonary infection (three patients), cerebral infection (five patients) and disseminated infection (one patient). The predominant (60%) species was Nocardia farcinica rather than the Nocardia asteroides complex. Treatment was started empirically, modified according to the antimicrobial susceptibility pattern, and then continued for 6-12 months. Overall mortality was 33%, with death being caused by the Nocardia infection in two cases.