Lignans form Linum species of sections Syllinum and Linum

KONUKLUGİL B. , Ionkova I., Vasilev N., Schmidt T., Windhövel J., Fuss E., ...More

Natural Product Research, vol.21, no.1, pp.1-6, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 1
  • Publication Date: 2007
  • Doi Number: 10.1080/14786410600798385
  • Title of Journal : Natural Product Research
  • Page Numbers: pp.1-6
  • Keywords: Linum, podophyllotoxin, 6-methoxypodophyllotoxin, 5 '-demethoxy-6-methoxy-podophyllotoxin, 4 '-demethyl-6-methoxypodophyllotoxin, 6-methoxypicropodophyllin, 5 '-demethoxy-6-methoxypicropodophyllin, justicidin B, isojusticidin B, CELL-CULTURES, PODOPHYLLOTOXIN


The aryltetralin lignans 6-methoxypodophyllotoxin, 5′-demethoxy-6-methoxypodophyllotoxin as well as the corresponding 8′-epimers 6-methoxypicropodophyllin, and 5′-demethoxy-6-methoxypicropodophyllin were isolated from suspension cultures of Linum cariense, and 4′-demethyl-6-methoxypodophyllotoxin together with 6-methoxypodophyllotoxin from plants of L. tauricum, which both belong to section Syllinum of the genus Linum. Cell cultures of L. altaicum, L. austriacum ssp. euxinum and L. lewisii belonging to section Linum accumulate the naphthalene lignans justicidin B and isojusticidin B. The different lignans were identified by HPLC and spectroscopic methods.