The effect of high-dose inhaled budesonide on lipid profile in asthmatic patients
General Pharmacology, cilt.27, sa.1, ss.89-90, 1996 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 27 Sayı: 1
- Basım Tarihi: 1996
- Doi Numarası: 10.1016/0306-3623(95)00119-0
- Dergi Adı: General Pharmacology
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.89-90
- Lokman Hekim Üniversitesi Adresli: Evet
Özet
1. We determined the effect of high doses of inhaled corticosteroid (budesonide, BUD, 1600 μg/day for 4 weeks) on fasting triglyceride, cholesterol and high-density lipoprotein (HDL)-cholesterol concentration in 11 asthmatic patients. 2. No significant change of serum fasting triglyceride concentrations was found before and after BUD therapy (p > 0.05). However, serum fasting cholesterol concentrations decreased slightly (p = 0.03) and HDL-cholesterol concentrations increased after BUD therapy for four weeks (p = 0.01). 3. These results suggest that high-dose BUD therapy does have minor effects on lipid metabolism after long periods of use in asthmatic patients.