The effect of high-dose inhaled budesonide on lipid profile in asthmatic patients

Yavuz Ö., Türktaş I., ÇEVİK C.

General Pharmacology, cilt.27, sa.1, ss.89-90, 1996 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 1
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1016/0306-3623(95)00119-0
  • Dergi Adı: General Pharmacology
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.89-90
  • Lokman Hekim Üniversitesi Adresli: Evet

Özet

1. We determined the effect of high doses of inhaled corticosteroid (budesonide, BUD, 1600 μg/day for 4 weeks) on fasting triglyceride, cholesterol and high-density lipoprotein (HDL)-cholesterol concentration in 11 asthmatic patients. 2. No significant change of serum fasting triglyceride concentrations was found before and after BUD therapy (p > 0.05). However, serum fasting cholesterol concentrations decreased slightly (p = 0.03) and HDL-cholesterol concentrations increased after BUD therapy for four weeks (p = 0.01). 3. These results suggest that high-dose BUD therapy does have minor effects on lipid metabolism after long periods of use in asthmatic patients.