Coenzyme Q10 and high-sensitivity C-reactive protein in ischemic and idiopathic dilated cardiomyopathy


Senes M., Erbay A. R. , Yilmaz F. M. , Topkaya B. C. , Zengi U., Dogan M., ...More

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol.46, no.3, pp.382-386, 2008 (Journal Indexed in SCI) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 3
  • Publication Date: 2008
  • Doi Number: 10.1515/cclm.2008.061
  • Title of Journal : CLINICAL CHEMISTRY AND LABORATORY MEDICINE
  • Page Numbers: pp.382-386
  • Keywords: antioxidants, cardiomyopathy, coenzyme Q10, C-reactive protein, heart failure, oxidative stress, CONGESTIVE-HEART-FAILURE, INCREASED OXIDATIVE STRESS, COA REDUCTASE INHIBITORS, CORONARY-ARTERY DISEASE, PROGNOSTIC VALUE, PLASMA, RADICALS, GLUTATHIONE, SUPEROXIDE, MARKER

Abstract

Background: Cardiomyopathy (CMP) is a common debilitating illness, associated with a high mortality and poor quality of life. There is extensive evidence from in vitro and animal experiments that CMP is a state of increased oxidative stress. Coenzyme Q10 (CoQ10) and high-sensitivity C-reactive protein (hs-CRP) are important markers to evaluate the oxidative stress and inflammatory status of patients with CMP.