Usporedba osteoimunoloških i mikrobioloških parametara ekstremno kratkih i dužih implantata u stražnjim dijelovima donje celjusti pod opterecenjem: Randomizirano klinicko istraživanje split-mouth Comparison of Osteoimmunological and Microbiological Parameters of Extra Short and Longer Implants Loaded in the Posterior Mandible: A Split Mouth Randomized Clinical Study


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Karci B., Oncu E.

Acta Stomatologica Croatica, vol.55, no.3, pp.238-247, 2021 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.15644/asc55/3/1
  • Title of Journal : Acta Stomatologica Croatica
  • Page Numbers: pp.238-247
  • Keywords: Dental Implants, Immunology, Microbiology, SHORT DENTAL IMPLANTS, GINGIVAL CREVICULAR FLUID, SINGLE-TOOTH RESTORATIONS, FOLLOW-UP, BONE, MM, METAANALYSIS, MULTICENTER, MICROBIOTA, DIAMETER

Abstract

© 2021 University of Zagreb. All rights reserved.Objectives: This study aimed to evaluate the levels of TNF-α, PGE2, RANKL, RANK, OPG, the markers of periimplant bone loss in peri-implant crevicular fluid obtained around standard and extra short implants. Moreover, the levels of putative oral pathogens were investigated in the submucosal biofilm samples. Material and Methods: The implants were divided into two groups according to their lengths: Standard (≥8 mm) and extra short (4 mm). A total of 60 implants were researched in 30 patients. The probing depth (PD), clinical attachment level (CAL), presence of bleeding on probing (BOP), 3-year survival rate (CSR), and bone loss (BL) were measured. Results: No statistically significant difference was found in the values of PD, CAL, BOP, CSR, and BL between the groups (P> 0.05). Total amounts of PGE2, TNF-α, RANKL, RANK, OPG, and RANKL/OPG were not statistically significantly different between the groups (P> 0.05). The abundance of F. nucleatum, T. forsythia, P. intermedia, P. gingivalis, S. oralis and T. denticola was compared between the groups and the results were not statistically significant (P> 0.05). Conclusion: The results of this study suggested that PGE2, TNF-α, RANKL, RANK, OPG, and RANKL/OPG in PICF, as well as microbiological parameters in submucosal biofilms, were similar between standard (≥8 mm) and extra short (4 mm) implants. Therefore, the implant length does not seem to influence the bone loss, levels of osteoimmunological and microbiological markers in the peri-implant tissues and survival rates.