Two new quinoline and tris(4-hydroxycinnamoyl)spermine derivatives from Microdesmis keayana roots

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Zamble A., Hennebelle T., ŞAHPAZ S., Bailleul F.

Chemical and Pharmaceutical Bulletin, cilt.55, sa.4, ss.643-645, 2007 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 4
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1248/cpb.55.643
  • Dergi Adı: Chemical and Pharmaceutical Bulletin
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.643-645
  • Anahtar Kelimeler: Pandaceae, Microdesmis keayana, tris(4-hydroxycinnamoyl)spermine, xanthoquininamide, VITRO ANTIPLASMODIAL ACTIVITY, PLANTS, CYTOTOXICITY
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Purification of a Microdesmis keayana hydromethanolic root extract led to the isolation of two new natural compounds, xanthoquininamide (6-hydroxyquinoline-4-carboxamide) and tris(4-hydroxycinnamoyl)spermine (N 5-(p-coumaroyl)-N1,N14-diferuloylspermine) which was named keayanine. Their structures were determined using spectroscopic analyses (ESI-MS, 1D- and 2D-NMR). © 2007 Pharmaceutical Society of Japan.