Akademik Veri Yönetim Sistemi
IV. Bio.Natural Conference, Lisbon, Portekiz, 14 - 16 Temmuz 2025, ss.16, (Özet Bildiri)
The realm of beauty products is witnessing a shift towards naturally derived
ingredients. These "natural cosmetics" utilize substances found in plants,
minerals, and other natural sources. A related category, "cosmeceuticals," goes
a step further by incorporating active ingredients that offer potential
therapeutic benefits for the skin, distinguishing them from traditional cosmetics
that primarily focus on hydration and aesthetics. The relatively new field of
"nanocosmetics" leverages nanotechnology to enhance the performance of
beauty and personal care products. This approach allows for improved delivery
and efficacy of active ingredients, often through the use of nanocarriers. These
carriers can encapsulate and transport specific substances to targeted areas
within the skin, maximizing their impact and minimizing potential side effects.
Nanocosmetics can also address multiple skin concerns simultaneously,
simplifying skincare routines by combining benefits such as hydration,
anti-aging, and sun protection into a single product. Not only in cosmetics, but
also in medical device formulations, nanoforms can be applied due to their
advantages.
Our research team has been actively involved in developing innovative
plant-based cosmeceuticals at laboratory scale. We employ rigorous
screening methods, including in vitro enzyme inhibition assays, in silico
molecular docking and toxicity assessments, along with the cell-based studies,
to identify potent plant extracts and natural compounds. For example, we have
successfully incorporated extracts from Cotinus coggygria into niosome,
nanofiber, and nanoemulgel formulations. Furthermore, we have developed a
patent-pending anti-acne formulation based on a blend of plant extracts
specifically targeting Propionibacterium acnes. In a separate study, we created polycaprolactone (PCL) electrospun nanofibers loaded with Cotinus coggygria extract and hyaluronic acid (HA) for wound healing applications.
This talk will highlight our most recent findings regarding the development of
these novel phyto-based cosmeceutical formulations.