The association of oxygen saturation, tomography findings and d-dimer levels in coronavirus disease 2019 patients
BLOOD COAGULATION & FIBRINOLYSIS, cilt.31, sa.8, ss.558-561, 2020 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 8
- Basım Tarihi: 2020
- Doi Numarası: 10.1097/mbc.0000000000000964
- Dergi Adı: BLOOD COAGULATION & FIBRINOLYSIS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
- Sayfa Sayıları: ss.558-561
- Anahtar Kelimeler: coronavirus disease 2019, d-dimer, oxygen saturation, CHEST CT, MORTALITY, FLUID
- Lokman Hekim Üniversitesi Adresli: Evet
Özet
Coronavirus disease is a highly contagious disease caused by systemic acute respiratory syndrome coronavirus 2 with high mortality rates. We aimed to evaluate the relationship between serum d-dimer levels and tomography findings at the time of admission in patients diagnosed with coronavirus disease 2019 (COVID-19). This study included 94 patients, 48 women (51%) and 46 men (49%), diagnosed by PCR method. Patients without any suspicious findings on thorax tomography and having oxygen saturation above 90% at the time of presentation were included as the first group. Patients with suspicious tomography findings but having oxygen saturation above 90% were designed as the second group, and patients with both suspicious tomography findings for COVID-19 and low oxygen saturation levels (<90%) at the time of admission were taken as the third group. Patients with oxygen desaturation were significantly older than the patients with normal oxygen saturations (P = 0.001). Patients with thorax tomography findings were having significantly higher d-dimer levels (P = 0.001). Patients with oxygen desaturation were having significantly higher d-dimer levels than the patients with normal oxygen saturations (P = 0.001). There was a significant negative correlation between oxygen saturation and d-dimer levels in all patients with and without tomography findings (r = -0.301, P = 0.016). Similarly, there was a significant positive correlation between the oxygen saturation and the lymphocyte count (r = 0.300, P < 0.017). Thorax tomography and d-dimer levels significantly correlate in patients with suspected COVID-19 admission. It should be kept in mind that patients with low oxygen saturation and high d-dimer levels may have serious lung involvement.