Akademik Veri Yönetim Sistemi
EUROPEAN ARCHIVES OF PAEDIATRIC DENTISTRY, cilt.25, sa.5, ss.1-13, 2024 (ESCI)
Purpose The aim of this study is to compare the efect of GSH (reduced glutathione) and KI (potassium iodide) on SDF(silver diamine fuoride) discolouration and dentine remineralisation.
Methods Sixteen primary molars were utilised, yielding 4 dentine specimens each. Three specimens per tooth were allocated:one as a control and the others to experimental groups. Initial microhardness measurements were taken from one remaining dentine specimen per tooth. Subsequently, all groups underwent exposure to a demineralisation solution. Colorimetryassessed specimen colour, and post-second microhardness measurements on demineralised specimens, treatments wereadministered as follows: group 1 (control, n=16): 38% SDF, group 2 (n=16): 38% SDF followed by KI, group 3 (n=16):38% SDF with 5% GSH added by weight. Following pH cycling across all groups, colorimetry reassessed 48 dentine specimens. Final microhardness measurements ensued, followed by statistical analysis. Normality was checked via Shapiro–Wilk,and homogeneity via Levene's test. Independent samples t test compared normally distributed groups; Mann–Whitney Ucompared non-normally distributed groups. ANOVA compared means of normally distributed groups, and Kruskal–Wallisfor non-normally distributed ones. Repeated measures ANOVA compared dependent groups with normal distribution, andFriedman test for non-normal. Post hoc Bonferroni analyses identifed signifcant diferences. IBM SPSS 25 was used toconduct analyses.
Results The mean ΔE* values for SDF and SDF+GSH groups were signifcantly higher than those of the SDF+KI group(p<0.05). Signifcant diferences in L* values during fnal colour measurement were noted between the SDF+KI group andboth SDF and SDF+GSH groups (p<0.05). Although mean remineralisation microhardness measurements were higherthan mean demineralisation microhardness measurements in all groups, statistical signifcance was observed only in theSDF and SDF+KI groups (p<0.05).
Conclusion The study found that the addition of 5% GSH by weight to SDF does not signifcantly afect discolouration.Moreover, the addition of 5% GSH to the SDF solution may have a minor impact on the remineralisation potential of SDF.The application of KI after SDF reduces discolouration and does not afect the expected remineralisation process.