Gazi Medical Journal, cilt.11, sa.4, ss.165-169, 2000 (Scopus)
Purpose: The aim of this study was to investigate the effects of five different types of dental local anaesthetics with or without a vasoconstrictor on blood glucose level, heart rate and blood pressure in otherwise healthy volunteers undergoing third molar operation. Methods: Sixty healthy volunteers divided into five groups took part and five different dental local anaesthetics, such as prilocaine 3%, lidocaine 2%, articain HCl 20 mg, articain HCl 40 mg or mepivacaine with vasoconstrictors were used. Heart rate and blood pressure were recorded 5 min before, and 5, 20 and 120 min after the injection of dental local anaesthetic. Blood glucose levels were measured concomitantly with heart rate and blood pressure records. Results: Blood glucose level, heart rate and blood pressure were stable and in significant changes were noted by the use of dental local anaesthetics during third molar operation. Conclusion: It is concluded that dental local anaesthetics can be used confidently in patients who are under stressful surgery up to a dosage of 2 ml in dental practice.