Successful treatment of chronic hiccup with baclofen in cancer patients

Şeker M. M. , AKSOY S., Özdemir N. Y. , Uncu D., Civelek B., Akinci M. B. , ...More

Medical Oncology, vol.29, no.2, pp.1369-1370, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1007/s12032-011-9910-3
  • Title of Journal : Medical Oncology
  • Page Numbers: pp.1369-1370
  • Keywords: Hiccup, Cancer, Chemotherapy, Baclofen


Chronic hiccup is an infrequent but distressing symptom in patients with advanced cancer. A series of drugs (chlorpromazine, haloperidol, nifedipine, metoclopramide, baclofen) have been used to treat hiccup without definitive results. Some authors have suggested a possible role of baclofen in the treatment of chronic hiccup. We report three cases of chronic hiccup in patients with cancer successfully treated with baclofen. © Springer Science+Business Media, LLC 2011.