Successful treatment of chronic hiccup with baclofen in cancer patients

Şeker M. M., AKSOY S., Özdemir N. Y., Uncu D., Civelek B., Akinci M. B., ...More

Medical Oncology, vol.29, no.2, pp.1369-1370, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1007/s12032-011-9910-3
  • Journal Name: Medical Oncology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1369-1370
  • Keywords: Hiccup, Cancer, Chemotherapy, Baclofen
  • Lokman Hekim University Affiliated: No


Chronic hiccup is an infrequent but distressing symptom in patients with advanced cancer. A series of drugs (chlorpromazine, haloperidol, nifedipine, metoclopramide, baclofen) have been used to treat hiccup without definitive results. Some authors have suggested a possible role of baclofen in the treatment of chronic hiccup. We report three cases of chronic hiccup in patients with cancer successfully treated with baclofen. © Springer Science+Business Media, LLC 2011.