Successful treatment of primary non-Hodgkin's lymphoma of the vagina with chemotherapy

Engin H., Türker A., Abali H., ÜNER A., GÜNALP G. S.

Archives of Gynecology and Obstetrics, vol.269, no.3, pp.208-210, 2004 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 269 Issue: 3
  • Publication Date: 2004
  • Doi Number: 10.1007/s00404-002-0350-3
  • Journal Name: Archives of Gynecology and Obstetrics
  • Journal Indexes: Scopus
  • Page Numbers: pp.208-210
  • Keywords: Cytotoxic chemotherapy, Follicular large B cell, Non-Hodgkin's lymphoma, Vagina
  • Lokman Hekim University Affiliated: No

Abstract

Introduction: The vagina as a primary site of malignant lymphoma in woman is extremely rare. Case report: We report here a 30-year-old patient with a primary vaginal non-Hodgkin's lymphoma stage IEA, follicular large cell of B lineage, with an excellent response to cytotoxic chemotherapy (CHOP) and event-free survival of 28 months. Conclusion: Primary involvement of the vagina can be successfully treated by pelvic irradiation, but in young women chemotherapy should be considered to preserve fertility, as well as quality of life.