Effect of in vitro hemolysis on 25 common biochemical tests

YÜCEL D., Dalva K.

Clinical Chemistry, cilt.38, sa.4, ss.575-577, 1992 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 4
  • Basım Tarihi: 1992
  • Doi Numarası: 10.1093/clinchem/38.4.575
  • Dergi Adı: Clinical Chemistry
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.575-577
  • Anahtar Kelimeler: acid phosphatase, lactate dehydrogenase, potassium, sample handling, variation, source of
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Clinical chemists frequently encounter hemolyzed samples. Our study examines the effects of hemolysis on the results of 25 common biochemical tests. We collected 60 15-mL blood samples from inpatients and outpatients and mechanically hemolyzed 10 mL of the samples in a two-step procedure. We classified serum from these samples as being nonhemolyzed, moderately hemolyzed, or severely hemolyzed and then performed 25 common biochemical tests. Statistical analysis of the results showed that hemolysis had the greatest effect on the lactate dehydrogenase, acid phosphatase, and potassium tests.