A randomized trial of four cycles of adjuvant AC (adriamycin plus cyclophosphamide) +/- two cycles of EP (etoposide plus cisplatin) in node positive patients with breast cancer


Icli F., AKBULUT H., Dincol D., Onur H., DEMİRKAZIK A., Cam R., ...More

ANNALS OF ONCOLOGY, vol.12, no.7, pp.1011-1013, 2001 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 12 Issue: 7
  • Publication Date: 2001
  • Doi Number: 10.1023/a:1011118004629
  • Journal Name: ANNALS OF ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1011-1013
  • Keywords: adjuvant chemotherapy, adriamycin, breast cancer, cisplatin, cyclophosphamide, etoposide, CHEMOTHERAPY, DOXORUBICIN
  • Lokman Hekim University Affiliated: No

Abstract

Background: Four cycles of AC have been accepted as the standard chemotherapy in breast cancer. In the present randomized study we aimed to assess the efficacy of adjuvant etoposide + cisplatin (EP) combination following four cycles of standard adriamycin + cyclophosphamide (AC) in premenopausal patients with operable breast cancer and axillary lymph node metastasis.