Akademik Veri Yönetim Sistemi
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, cilt.40, sa.6, ss.303-309, 2012 (Scopus)
Objective: Low-flow anaesthesia has become increasingly common by using modern anaesthesia devices. We aimed to compare anaesthesia with low flow and high fresh gas flows in children. Methods: Forty children in the ASA I-II groups, aged 5-15 years who were operated for upper and lower extremities and operation times between two and four hours, were included in this study. During the operation, 4-6% desflurane, 2 L min-1 N2O and 2 L min-1 O2 were given to the low dose group throughout the first 10 minutes (n=20). Afterwards, 50% O2, 50% N2O, 4-6% desflurane were given as one MAC. In the high flow group (n=20) 4-6% desflurane, 2 L min-1 N2O and 2 L min-1 O2 were given throughout the operation. Inspiratory and expiratory concentrations of O2, CO2, N2O and desflurane, vital parameters, BIS and MAC were measured. During the anaesthesia period, extubation period, and 24 hours after surgery arterial blood gas samples were taken. Results: Desflurane amount was 235±97 mL in the high flow group, and 106±26 mL in the low flow group. Although there were significant differences between the two groups in terms of inspired and expired O2, CO2, desflurane concentrations, and MAC levels, they were within clinically acceptable ranges. There was clinically no difference between the two groups. Lactate levels were higher in the low flow group (T1-T8 periods). There were no differences between the two groups in peroperative and recovery hemodynamics, arterial blood gas parameters, liver and kidney function, postoperative recovery period (extubation and orientation time). Conclusion: Our results show that low-flow anaesthesia, with the use of appropriate techniques and devices, close monitoring of blood gases and lactate levels, can be applied safely in children.