Non-acidic mediated friedel-craft reaction of thiophene using EtAlCl 2
Asian Journal of Chemistry, vol.25, no.15, pp.8772-8774, 2013 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 25 Issue: 15
- Publication Date: 2013
- Doi Number: 10.14233/ajchem.2013.15607
- Journal Name: Asian Journal of Chemistry
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.8772-8774
- Keywords: Thiophene, Acylation, Alkyl Lewis acid, Electrophilic aromatic substitution, BRIDGED FERROCENES, ACYLATION, CATALYSTS, EFFICIENT
- Open Archive Collection: AVESIS Open Access Collection
- Lokman Hekim University Affiliated: No
Abstract
Since alkyl Lewis acids are BrØnsted bases, they give a non-acidic reaction media. In this context, acylation of thiophene is investigatedin the presence of EtAlCl2 and non-acidic media. Besides 8 examples of thiophene, one example for pyrrole is synthesized in moderate tohigh yields (up to 99 %).