Stability of antimicrobial decapeptide (KSL) and its analogues for delivery in the oral cavity

Na D. H., Faraj J., Capan Y., Leung K. P., DeLuca P. P.

PHARMACEUTICAL RESEARCH, vol.24, no.8, pp.1544-1550, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 8
  • Publication Date: 2007
  • Doi Number: 10.1007/s11095-007-9274-8
  • Journal Name: PHARMACEUTICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1544-1550
  • Keywords: antimicrobial peptide, antiplaque agent, chewing gum, peptide analogue, stability, ANTI-PLAQUE AGENTS, CHEWING GUM, MASS-SPECTROMETRY, CHLORHEXIDINE, MICROSPHERES, PREVENTION, PEPTIDES, RELEASE
  • Lokman Hekim University Affiliated: No

Abstract

Purpose. To investigate the stability of KSL, an antimicrobial decapeptide, and its analogues, in human saliva and simulated gastric fluid for delivery in the oral cavity.