AMERICAN JOURNAL OF NEURORADIOLOGY, vol.25, no.1, pp.108-111, 2004 (SCI-Expanded)
BACKGROUND AND PURPOSE: Apparent diffusion coefficient (ADC) values derived from diffusion-weighted MR imaging are useful measurements for assessment of cellular alterations in pathologic conditions of the brain. In this study, two radiologists independently quantitated ADCs and region-of interest sizes in prespecified locations of human brain to test interobserver ADC variance and the effect of varying ROI sizes on ADC differences.