Akademik Veri Yönetim Sistemi
European Society of Clinical Pharmacy Aberdeen Symposium 2023, Aberdeen, İngiltere, 31 Ekim - 02 Kasım 2023, cilt.46, sa.45, ss.255, (Özet Bildiri)
Background and objective: In Turkey there is a lack of ‘Clinical Pharmacy Unit’s in private hospitals established to provide structured pharmaceutical care to patients. Our aim is to provide and evaluate the outcomes of certain clinical pharmacy services at inpatient clinics of Infectious Diseases, Internal Diseases and Chest Diseases Departments of a private university hospital through the establishment of a Clinical Pharmacy Unit.
Method: Randomized controlled prospective study in a 216-bed university hospital; once hospitalized intervention group received: identification of and intervention to drug-related problems, education on discharge medications and new medicine service; control group received: usual care. As follow-up all patients would receive three bimonthly clinical tele-pharmacy services including monitorization of relevant parameters such as number of hospitalizations, outpatient and emergency department admissions, drug therapy changes, medication adherence, drug knowledge.
Main outcome measures: Comparison of monitoring parameters between the intervention and control groups and descriptive analysis of drug-related problems.
Results: Patients enrolled in the study were randomized to control (n = 44, 6 were lost to follow-up) or intervention group (n = 50). This preliminary report describes the outcomes of the first bi-monthly follow-up of 94 patients [female: 60.2%; mean (SD) age: 70.96 (14.5)]. Baseline characteristics such as mean (SD) number of chronic diseases [3.3 (1.5)] and medications [6.8 (3.6)] were similar for both groups. On follow-up intervention group had higher medication adherence and drug knowledge scores than the control group [median (IQR): 0 (1) vs. 2 (2); p\0.05; 6 (2) vs 4 (1); p\0.05, respectively]. Number of outpatient clinic admissions was higher in the control group compared to the intervention group [1 (2) vs 0 (1); p\0.05].
Number of hospitalizations, emergency department admissions and parameters related with drug therapy changes were similar for both groups. A total of 101 drug-related problems were identified in 36 patients in the intervention group; 81.2% of these problems were intervened and 84.1% of the interventions were accepted by the physicians or patients.
Conclusion: These results demonstrate that establishment of a ‘Clinical Pharmacy Unit’ and provision of structured pharmaceutical care services improved medication knowledge and adherence of patients besides contribution to safe and effective drug therapy through drug-related problem identification and resolution.