Comparison of analgesic effects of lornoxicam and tramadol during septoplasty Septoplasti cerrahisinde lornoksikam ve tramadolün analjezik etkilerinin karşilaştirilmasi


Artukoǧlu F., ÇELEBİ N., CANBAY Ö., Çeliker V., AYPAR Ü.

Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, cilt.34, sa.6, ss.377-385, 2006 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 6
  • Basım Tarihi: 2006
  • Dergi Adı: Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.377-385
  • Anahtar Kelimeler: Lornoxicam, Nasal septoplasty, Sedation, Tramadol
  • Lokman Hekim Üniversitesi Adresli: Evet

Özet

Aim: Performing nasal septoplasty under local anesthesia and sedation has its advantages like loss operational bleeding and decreased hospitalization time, when compared with general anesthesia. Using the new parenteral Non-Steroidal Anti-inflammatory Drug (NSAID) lornoxicam may be effective as the sole analgesic during septoplasty. Our aim was to compare intraoperative and postoperative analgesic efficacy of lornoxicam with tramadol, as the sole analgesic during septoplasty. Material and Method: Following Institutional Ethical Committee approval, 41 patients between ages of 16 and 50 were included in this randomized study. Patients were randomized into 2 groups. Group T received 3.5 mg iv midazolam and 100 mg iv tramadol; Group L received 3.5 mg iv midazolam and 16 mg iv lornoxicam, 30 minutes prior to the operation. Intraoperative surgical field bleeding scores, Verbal Rating Scale for Pain (VRS) scores, any need of extra analgesics or turning into general anesthesia, as well as preoperativo and postoperative complications were recorded. Postoperatively, patients' need of analgesics, any complications and complaints, 24th hour pain VRS scores, as well as their overall satisfaction with the operation were asked through telephone calls. Results: Group T and Group L were statistically different from each other according to number of patients that required general anesthesia and surgical field bleeding scores. Intraoperativc need of extra analgesics and intraoperativc pain VRS scores were similar between two groups. For postoperative measures, two groups were; similar according to complaints, need of analgesics, postoperative pain scores and overall satisfaction with the operation. Intraoperative usage of 16 mg iv lornoxicam, as the sole analgesic, is better tolerated than 100 mg iv tramadol by the patients, during nasal septoplasty under local anesthesia and sedation. Conclusion: Lornoxicam is also, as effective and safe as tramadol for providing postoperative analgesia during the first 24 hours after administration.