Synthesis of new ferrocenyl-substituted aziridines via the Gabriel-Cromwell reaction
Synthetic Communications, cilt.35, sa.8, ss.1067-1076, 2005 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 35 Sayı: 8
- Basım Tarihi: 2005
- Doi Numarası: 10.1081/scc-200054207
- Dergi Adı: Synthetic Communications
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1067-1076
- Anahtar Kelimeler: alpha-bromoacryloyferrocene, alpha-bromocrotonoylferrocene, aziridines, ferrocenylenones, Gabriel-Cromwell method, 1,3-DIPOLAR CYCLOADDITIONS, ASYMMETRIC-SYNTHESIS, AZOMETHINE YLIDES, CHIRAL AZIRIDINES, ACID-DERIVATIVES, AMINO-ACIDS, ALPHA-AMINO, AZIRIDINE-2-CARBOXYLATES, AUXILIARY, EFFICIENT
- Lokman Hekim Üniversitesi Adresli: Hayır
Özet
The Gabriel-Cromwell method is applied successfully in the synthesis of ferrocenyl-substituted aziridines. Acryloyl- and crotonoylferrocenes are brominated first and then reacted with benzylamine, diisopropylamine, and furfurylamine in the presence of triethylamine. The aziridines are obtained in more than 90% isolated yields. Copyright © Taylor & Francis, Inc.