Current Therapeutic Research-Clinical And Experimental, vol.68, no.3, pp.184-190, 2007 (SCI-Expanded)
Article / Article
Current Therapeutic Research-Clinical And Experimental
Science Citation Index Expanded (SCI-EXPANDED), Scopus
experimental endophthalmitis, fluoroquinolone, ofloxacin, lomefloxacin, lens, animal study, rabbit, TOPICALLY APPLIED CIPROFLOXACIN, LIQUID-CHROMATOGRAPHIC ASSAY, AQUEOUS-HUMOR LEVELS, VITREOUS-HUMOR, PENETRATION, LEVOFLOXACIN, NORFLOXACIN, FLUOROQUINOLONES, 0.3-PERCENT
Lokman Hekim University Affiliated:
Background: Bacterial endophthalmitis is a serious complication of ocular surgery and penetrating trauma. The primary causative organisms are strains of Staphylococcus aureus and Staphylococcus epidermidis. Fluoroquinolones are widely used to treat endophthalmitis. There are a few studies on the penetration of fluoroquinolones into the lens in inflamed eyes. A literature search did not identify any data regarding penetration of topical ofloxacin into the lens in normal and inflamed eyes.