The effect of the use of azelastine HCL and triamcinolone acetonide on symptoms in patients with seasonal allergic rhinitis Mevsi̇msel allerji̇k ri̇ni̇tte topi̇kal azelasti̇n HCL i̇le tri̇amsi̇nolone asetoni̇de kullaniminin semptomlar üzeri̇ne etki̇si̇ni̇n araştirilmasi

Iriz A., Karabulut H., Daǧli M., GÖÇER C., DURSUN E., Eryilmaz A.

Gazi Medical Journal, cilt.20, sa.4, ss.173-175, 2009 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 4
  • Basım Tarihi: 2009
  • Dergi Adı: Gazi Medical Journal
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.173-175
  • Anahtar Kelimeler: Allergic rhinitis, Azelastine HC1, Triamcinolone acetonide
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Purpose: The use of antihistamine and topical nasal steroids represents the cornerstone of the pharmacologic treatment of allergic rhinitis. Antihistamines can be used topically or orally. This study compared the efficiency of intranasal azelastine HC1 and intranasal triamcinolone acetonide on symptoms in patients with seasonal allergic rhinitis. Materials and Methods: A total 20 adult patients 18-45 years old were enrolled in the study. Prick test results of all patients were highly positive. All patients took oral levocetirizine 2-HC1, with the first 10 patients taking topical azelastine HC1 and the other 10 patients taking topical triamcinolone acetonide. We determined total symptom scores of all patients through daily questionnaires. Analysis of patient based symptom scores and daily symptom scores for the first and last 15 days were evaluated. Results: Azelastine topical spray was ineffective on the symptoms of patients with seasonal allergic rhinitis. However, topical triamcinolone acetonide achieved greater relief of allergic rhinitis' symptoms in the first and last 15 days. Conclusion: The use of topical corticosteroids is more effective than that of topical antihistamines.