Effect of plasma NOx values on cardiac function in obese hypertensive and normotensive pediatric patients


Akcaboy M., KULA S., Goktas T., Nazhel B., TOKGÖZ S., Celik N., ...More

PEDIATRIC NEPHROLOGY, vol.31, no.3, pp.473-483, 2016 (Peer-Reviewed Journal) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1007/s00467-015-3223-2
  • Journal Name: PEDIATRIC NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.473-483
  • Keywords: Plasma NOx, Hypertension, Obese, Children, Echocardiography, AMBULATORY BLOOD-PRESSURE, LEFT-VENTRICULAR HYPERTROPHY, SERUM URIC-ACID, METABOLIC SYNDROME, NITRIC-OXIDE, CARDIOVASCULAR-DISEASE, INSULIN-RESISTANCE, DIASTOLIC FUNCTION, CHILDHOOD OBESITY, TURKISH CHILDREN

Abstract

Background Hypertension (HT) is a major comorbidity of obesity that is associated with an increased risk of cardiovascular disease and higher mortality. The aim of our study was to evaluate cardiac function in obese hypertensive (OHT) and obese normotensive (ONT) pediatric patients and determine the effects of plasma nitric oxide (NOx) values on cardiac function, while demonstrating the role of plasma NOx in HT in obese pediatric patients.