New class of steroidal alkaloids from Fritillaria imperialis

Akhtar M., Atta-ur-Rahman A., Choudhary M., Sener B., Erdogan İ., Tsuda Y.

Phytochemistry, cilt.63, sa.1, ss.115-122, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 1
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0031-9422(02)00569-1
  • Dergi Adı: Phytochemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.115-122
  • Anahtar Kelimeler: Fritillaria imperialis, impranine, dihydroimpranine, fetisinine, impranane-type steroidal alkaloids
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Two members of a new class of C-nor-D-homo steroidal alkaloids, impranine (1) and dihydroimpranine (2) along with a new pyridyl-pregnane-type steroidal alkaloid, fetisinine (3) and a known base, korsevine (4) were isolated from the bulbs of Fritillaria imperialis. The structures of the compounds were established on the basis of spectroscopic techniques and some chemical transformations. Compounds 1 and 2 form a new class of steroidal alkaloids, named as "impranane." © 2003 Elsevier Science Ltd. All rights reserved.