The effects of nocturnal blood pressure patterns and autonomic alterations on erectile functions in patients with hypertension

Yuvanc E., Dogru M. T., Simsek V., Kandemir H., TUĞLU D.

Urology Journal, cilt.16, sa.2, ss.198-204, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 2
  • Basım Tarihi: 2019
  • Dergi Adı: Urology Journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.198-204
  • Anahtar Kelimeler: Erectile dysfunction, non-dipper hypertension, sympathetic overactivity, heart rate variability, IIEF, TARGET ORGAN DAMAGE, LEFT-VENTRICULAR MASS, INTERNATIONAL INDEX, DYSFUNCTION, DIPPER, FALL, MANAGEMENT
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

© 2019, Urology and Nephrology Research Centre.Purpose: Hypertension (HT) is known to be of the main risk factors for erectile dysfunction (ED). But non-dipping (< %10 drop in the night) of HT is not investigated truly. The aim of this study was to test the hypothesis that the non-dipper hypertensive patients are more prone to develop erectile dysfunction. Materials and Methods: This was a cross-sectional clinical study. 70 HT patients diagnosed by Ambulatory blood pressure monitoring (ABPM) were classified into 3 groups (No ED, mild to moderate and severe) according to their International Index of Erectile Function (IIEF) scores. All three groups were compared for their dipping status by ABPM, heart rate variability (HRV) by holter monitoring. Results: In our study non-dipper hypertensives had statistically more erectile dysfunction (P = 0.004). Also severe ED patients with non-dipping pattern had decreased dipping blood pressure levels then those of ED(-) patients with non-dipping HT (P = .003) Conclusion: Autonomic dysfunction especially sympathetic overactivity is associated with both non dipping pattern of HT and erectile dysfunction as a common pathologic pathway, besides there might be an association between ED and non dipping HT.