Cardiac and respiratory changes in the medium term after lung resection Akciʇer rezeksiyonu sonrasi orta vadede kalp ve solunum fonksiyonlarmda deʇişiklikler


KAPLAN T. , Tanindi A., Uʇurlu M., Han S. , Töre H. F.

Turk Kardiyoloji Dernegi Arsivi, vol.43, no.5, pp.434-442, 2015 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.5543/tkda.2015.58566
  • Title of Journal : Turk Kardiyoloji Dernegi Arsivi
  • Page Numbers: pp.434-442
  • Keywords: Lung resection, echocardiography, Doppler, pneumonectomy, right ventricular function

Abstract

© 2015 Türk Kardiyoloji Derneʇi.Objective: The aim of this study was to assess the cardiac and respiratory functions at the 6th postoperative month, in lung cancer patients undergoing segmentectomy/lobectomy or pneumonectomy. Methods: Thirteen segmentectomy/lobectomy and 5 pneumonectomy patients with lung cancer were consecutively enrolled between April 2012 and February 2014. All patients underwent respiratory function tests and transthoracic echocardiography preoperatively and at 6 months postoperatively. Results: Left ventricular functions were unchanged postoperatively. In the segmentectomy/lobectomy group, there were no changes in right ventricular fractional area change (RVFAC) or tricuspid annular plane systolic excursion (TAPSE). However, TAPSE decreased from 19 (17-21) to 15.5 (14-16) in pneumonectomy patients (p=0.04). RVFAC was 59.5 (58-61) preoperatively and 59 (58-61) at 6 months postoperatively (p=0.049). Neither group showed differences in pulmonary acceleration time or diastolic and systolic eccentricity indices after operation. Tissue Doppler imaging (TDI) revealed no deterioration in left ventricular functions, but right ventricular diastolic functions (tricuspid E′/A′) were impaired in both groups. Right ventricular S′, showing the systolic function, was slightly decreased in the pneumonectomy group, in addition to a decrease in isovolumic velocity and isovolumic acceleration (IVA). Only IVA was decreased, from 2.33 (1.79-3.14) to 2.17 (1.73-3.01) (p=0.001), in segmentectomy/lobectomy group. Conclusion: Segmentectomy/lobectomy should be preferred over pneumonectomy when possible. Tissue Doppler imaging may be routinely used as a part of echocardiographic evaluation in patients with a higher risk of right ventricular dysfunction in order for these patients to be candidates for a closer cardiovascular follow-up.