Catalytic enantioselective addition of diethylzinc to aldehydes using aziridine based chiral ligands

BULUT A., Aslan A., Izgü E. Ç., DOĞAN Ö.

Tetrahedron Asymmetry, cilt.18, sa.8, ss.1013-1016, 2007 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 8
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.tetasy.2007.04.013
  • Dergi Adı: Tetrahedron Asymmetry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1013-1016
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

The readily available ferrocenyl substituted aziridinylmethanol 1 (FAM-1) was used as a chiral catalyst in the diethylzinc addition reaction to aromatic and aliphatic aldehydes to give secondary alcohols in high yields and up to 99% enantiomeric excess at room temperature. The catalyst can be recovered and used without losing its activity. © 2007 Elsevier Ltd. All rights reserved.