Macrolide Resistance Determinants of Invasive and Noninvasive Group B Streptococci in a Turkish Hospital

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Acikgoz Z. C. , Almayanlar E., Gamberzade S., Gocer S.

Antimicrobial Agents and Chemotherapy, vol.48, no.4, pp.1410-1412, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 4
  • Publication Date: 2004
  • Doi Number: 10.1128/aac.48.4.1410-1412.2004
  • Title of Journal : Antimicrobial Agents and Chemotherapy
  • Page Numbers: pp.1410-1412


Macrolide resistance in 156 consecutive group B streptococcal isolates was investigated. Thirty-five isolates (22.4%) had inducible (80%) or constitutive (20%) erythromycin resistance. The genes responsible were erm(B), erm(A) subclass erm(TR), and erm(B) plus erm(TR) in 62.9, 2.9, and 8.6% of isolates, respectively. Nine isolates (25.7%) harbored neither mef nor detectable erm genes.