Medicinal plants used in the treatment of human immunodeficiency virus

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Salehi B., Anil Kumar N. V., Şener B., Sharifi-Rad M., KILIÇ M., Mahady G. B., ...Daha Fazla

International Journal of Molecular Sciences, cilt.19, sa.5, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 19 Sayı: 5
  • Basım Tarihi: 2018
  • Doi Numarası: 10.3390/ijms19051459
  • Dergi Adı: International Journal of Molecular Sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: acquired immune deficiency syndrome, phytochemistry, pharmacognosy, antiviral, drug discovery, ANTI-HIV ACTIVITY, TYPE-1 REVERSE-TRANSCRIPTASE, INHIBITORY NATURAL-PRODUCTS, TRADITIONAL CHINESE MEDICINE, ACTIVITY IN-VITRO, AIDS AGENTS, ANTIVIRAL ACTIVITY, ESSENTIAL OILS, TRIPTERYGIUM-WILFORDII, AQUEOUS EXTRACTS
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

© 2018 by the authors. Licensee MDPI, Basel, Switzerland.Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa. There have been very promising developments in the treatment of HIV with anti-retroviral drug cocktails. However, drug resistance to anti-HIV drugs is emerging, and many people infected with HIV have adverse reactions or do not have ready access to currently available HIV chemotherapies. Thus, there is a need to discover new anti-HIV agents to supplement our current arsenal of anti-HIV drugs and to provide therapeutic options for populations with limited resources or access to currently efficacious chemotherapies. Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines, including anti-HIV agents. This review presents a survey of plants that have shown anti-HIV activity, both in vitro and in vivo.