Prolonged usage of intravaginal clindamycin cream combined with ampicillin for the management of PPROM-a case report PPROM yönetiminde uzamış intravajinal klindamisin kremin ampisilinle birlikte kullanımı - bir olgu sunumu

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Ercan C. M., Aydoǧan Ü., Karaşahin K. E., ALANBAY İ., Başer I.

Journal of the Turkish German Gynecology Association, vol.12, no.2, pp.124-126, 2011 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 2
  • Publication Date: 2011
  • Doi Number: 10.5152/jtgga.2011.28
  • Journal Name: Journal of the Turkish German Gynecology Association
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.124-126
  • Keywords: PPROM, Clindamycin vaginal cream, chorioamninitis, PRETERM PREMATURE RUPTURE, LABOR
  • Lokman Hekim University Affiliated: No

Abstract

Prolonged PPROM may be catastrophic both for the mother and fetus due to ascending infections. The decision was expectant management in the setting of a spontaneous preterm premature rupture of membranes (PPROM) case and the prevention of chorioamnionitis was essential. We aimed to describe maternal and neonatal outcomes in expectant management of PPROM beginning from the 24th gestational week (GW) of pregnancy up to the 34th week under treatment with continuous usage of intravaginal clindamycin cream. We concluded that expectant active management of PPROM with antibiotics may be a suitable treatment option in carefully selected patients after receiving the patient's approval. Intravaginal clindamycin cream may be combined with systemic antibiotics (ampicillin and erythromycin) and may be a maintenance single drug for the prophylaxis of ascending vaginal infections.