Subcorneal pustular dermatosis "Sneddon-Wilkinson disease": A case report Subkorneal püstüler dermatoz "Sneddon-Wilkinson hastaliǧi": Bir olgu sunumu

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Şahin A., Edgüer E. Y., ASTARCI H. M., Ekşioǧlu H. M.

Turkderm Deri Hastaliklari ve Frengi Arsivi, vol.51, no.1, pp.21-23, 2017 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.4274/turkderm.22755
  • Journal Name: Turkderm Deri Hastaliklari ve Frengi Arsivi
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.21-23
  • Keywords: Subcorneal pustular dermatosis, Sneddon-Wilkinson disease, neutrophilic dermatosis
  • Lokman Hekim University Affiliated: No


© Telif Hakki 2017 Deri ve Zührevi Hastaliklar Derneǧi.Subcorneal pustular dermatosis (SPD), first described by Sneddon and Wilkinson in 1956, is rare, chronic, and relapsing dermatosis. Mostly, it affects women aged 40-50-years. It is characterized by grouped, annular, circinate, serpiginous, and sterile pustules on normal or erythematous ground. Lesions tend to involve intertriginous areas, the trunk, and extremities symmetrically. The etiology is not known; it has been suggested that it is a reactive neutrophilic dermatosis. In this report, we present a 71-year-old female who presented with lesions involving mostly intertriginous areas and received the clinical and histopathological diagnosis of SPD based on direct immunofluorescence assay. The patient was treated successfully with topical mupirocin 2% pomade, 1% blue de metylene, and oral macrolid 1 gr/day while being investigated for gammopathy and myeloproliferative diseases and waiting for biopsy results. After the biopsy results were obtained, the treatment of the patient continued with clobetasol 17-propionate 0.05%, colchium dispert 2×0.5 mg and dapsone 100 mg/day. The case was evaluated in the light of the relevant literature.