Akademik Veri Yönetim Sistemi
Turk Hijyen ve Deneysel Biyoloji Dergisi, cilt.70, sa.2, ss.75-102, 2013 (Scopus)
Insecticides have a great importance in the increase of agricultural productivity and maintaining of public health. However, they can cause serious poisoning cases and even deaths at times due to accidental, intentional or occupational exposures. Thus insecticide poisoning cases are encountered frequently in Turkey as well as throughout the world. The first part of this review focused on the toxicological profiles of various insecticide groups (organophosphates, organochlorine insecticides, pyrethrines, pyrethroids, amitraz and other insectides (avermectines, diethyl-m-toluamid (DEET) and neonicotinik acid derivatives), and diagnosis and treatment of poisoning with those insecticides marketed in Turkey. In the second part, the studies on insecticide poisonings which were conducted in Drug and Poison Centers, Institutes of Forensic Science, Departments of Forensic Medicine, University and State Hospitals and Medical Centers in Turkey were evaluated with the aim of contributing the whole picture of the situation in Turkey. In review of these reports it was found that the most frequently occurred cases resulted from exposures with organophosphate compounds, and females were more vulnerable than males. It is noteworthy that there are numerous reports in Turkey regarding poisoning cases with amitraz, which was used mostly as a veterinary drug, especially in children despite no cases in the developed countries. On the other hand, poisoning cases with banned organochlorine insecticides have been thought to be caused by the insufficiency of necessary measures and controls that have not been taken by regulatory authorities and manufacturers. The conclusions on consumption of insecticides in agricultural production, storing, and intentional or other modes, and recommendations on the correct and safe production and use of insecticides, along with the protective measures to be taken against poisonings with these compounds, were listed in the last part of the review.