The relationship between Vitamin D and vasomotor symptoms during the postmenopausal period

Arslanca T., KORKMAZ H., Banu Arslanca S., PEHLİVANOĞLU B., ÖZGAN ÇELİKEL Ö.

Clinical Laboratory, cilt.66, sa.7, ss.1285-1290, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66 Sayı: 7
  • Basım Tarihi: 2020
  • Doi Numarası: 10.7754/clin.lab.2019.191116
  • Dergi Adı: Clinical Laboratory
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1285-1290
  • Anahtar Kelimeler: vitamin D, menopause, hot flashes, QUALITY-OF-LIFE, HOT FLASHES, D DEFICIENCY, MENOPAUSE, WOMEN, THERAPY, FLUSHES, TRANSITION
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

© 2020 Verlag Klinisches Labor GmbH. All rights reserved.Background: During the postmenopausal period, hot flashes are frequent symptoms and might impact quality of life. Vitamin D deficiency is commonly seen in this period. This study aims to assess the association between vitamin D deficiency and hot flashes. Methods: Two hundred ten postmenopausal women were recruited. The participants were divided into two groups: Group 1 consisted of postmenopausal women with hot flashes (n = 104), and Group 2 included the participants without hot flashes (n = 106). Results: The comparison of the two groups concerning vitamin D level showed that 52 patients Group 1 had vitamin 25(OH)D levels below 20 ng/mL, whereas only 25 patients in Group 2 (p < 0.001). After adjusting for age and menopause duration, there was also a significant difference between groups (21.65 vs. 34.17, respectively, p < 0.001). In multiple regression analysis, one unit decrease of vitamin 25(OH)D (1 - 0.941 = 0.059) increased the risk of hot flashes by 5.9%. Conclusions: The decreases of vitamin D levels were significantly associated with hot flashes in postmenopausal women independent of age and menopause duration.