Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility

Boynukalin F. K., ESİNLER İ., GÜVEN S., GÜNALP G. S.

Archives of Gynecology and Obstetrics, cilt.286, sa.6, ss.1577-1580, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 286 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1007/s00404-012-2476-2
  • Dergi Adı: Archives of Gynecology and Obstetrics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1577-1580
  • Anahtar Kelimeler: ART, Hyaluronan binding assay, Intrauterine insemination (IUI), Sperm quality
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Purpose: To investigate the relationship between hyaluronan binding (HB) assay and pregnancy rates in intrauterine insemination (IUI) cycles. Methods: This prospective cohort study was done in Hacettepe University, a tertiary care center for reproductive medicine. Seventy-one consecutive couples who suffered from unexplained infertility and underwent controlled ovarian hyperstimulation (COH) and IUI were enrolled into the study. Results: From the 71 IUI patients, the clinical pregnancy rate was 14.1 % (10 of 71). HB ratio from the overall patient number was 48.6 ± 25.9. The mean HB ratio in pregnant and non-pregnant groups was comparable (50.2 ± 25.2 vs. 48.3 ± 26.2, respectively, p > 0.05). Conclusions: Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility. © 2012 Springer-Verlag.