Novel Piperazine Amides of Cinnamic Acid Derivatives as Tyrosinase Inhibitors

GÜR MAZ, ZEHRA; ŞENOL DENİZ, FATMA; Shekfeh, Suhaib; ERDOĞAN ORHAN, İLKAY; BANOĞLU, ERDEN; ÇALIŞKAN, BURCU

doi:10.2174/1570180815666180420105652

Novel Piperazine Amides of Cinnamic Acid Derivatives as Tyrosinase Inhibitors

GÜR MAZ Z. T., ŞENOL DENİZ F. S., Shekfeh S., ERDOĞAN ORHAN İ., BANOĞLU E., ÇALIŞKAN B.

LETTERS IN DRUG DESIGN & DISCOVERY, vol.16, no.1, pp.36-44, 2019 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 16 Issue: 1
Publication Date: 2019
Doi Number: 10.2174/1570180815666180420105652
Journal Name: LETTERS IN DRUG DESIGN & DISCOVERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.36-44
Keywords: Ferulic acid, cinnamic acid, piperazine, tyrosinase, docking, huntington's diseases, MUSHROOM TYROSINASE, ANALOGS, DOCKING, AGENTS, DRUGS
Lokman Hekim University Affiliated: No

Abstract

Background: A series of novel cinnamic acid piperazine amide derivatives has been designed and synthesized, and their biological activities were also evaluated as potential tyrosinase inhibitors.