Assessment of LXR alpha agonist activity and selective antiproliferative efficacy: a study on different parts of Digitalis species
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.44, no.6, pp.745-751, 2019 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 44 Issue: 6
- Publication Date: 2019
- Doi Number: 10.1515/tjb-2018-0280
- Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.745-751
- Lokman Hekim University Affiliated: No
Abstract
Objective: Aerial parts and roots of three Digitalis species (Digitalis davisiana Heywood, Digitalis viridiflora Lindley and Digitalis grandiflora Miller; Plantaginaceae) were investigated from the viewpoint of cytotoxicity to identify the biologically active parts. Playing a role in cell proliferation and tumor growth, LXR alpha agonist activity also has become of interest to researchers investigating its relationship with the cytotoxicity.