Plasma levels of zinc, copper, and ceruloplasmin in patients after undergoing laparoscopic adjustable gastric banding

Böyük A., BANLI O., Gümüş M., Evliyaoğlu O., Demirelli S.

Biological Trace Element Research, vol.143, no.3, pp.1282-1288, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 143 Issue: 3
  • Publication Date: 2011
  • Doi Number: 10.1007/s12011-011-8965-5
  • Journal Name: Biological Trace Element Research
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1282-1288
  • Keywords: Laparoscopic adjustable gastric banding, Nutritional deficiencies, Trace elements, Obesity, BARIATRIC SURGERY, NUTRITIONAL CONSEQUENCES, FOLLOW-UP, MICRONUTRIENT DEFICIENCIES, OBESITY, BYPASS, GASTROPLASTY, SERUM
  • Lokman Hekim University Affiliated: No


Laparoscopic adjustable gastric banding (LAGB) causes significant weight loss in morbidly obese adults. However, its consequences on nutritional status still remain unclear. There are a few studies determining the nutritional status after LAGB and none have focused on the serum levels of zinc (Zn), copper (Cu), and ceruloplasmin (CP). We aimed to investigate the effects of LAGB surgery on plasma Zn, Cu, and CP levels. Thirty patients with LAGB with morbid obesity were included. Blood samples were collected preooperatively and in the postoperative third month to determine plasma Zn, Cu, and CP levels. The mean preoperative and postoperative body mass indexes (BMI) were 44.9 ± 7.4 kg/m 2 and 44.1 ± 6.5 kg/m 2 , respectively. The mean weight loss was 12.9 ± 3.3 kg at the postoperative third month. The postoperative Zn (500 ± 130 ng/ml), Cu (280 ± 80 ng/ml), and CP (23.9 ± 8.8 mg/dl) values were statistically significantly lower than the preooperative Zn (740 ± 230 ng/ml), Cu (370 ± 80 ng/ml) and CP (33.3 ± 15.7 mg/dl) levels (p < 0.05). Decreases in the plasma levels of Zn, Cu, and CP were seen postoperatively following LAGB surgery. The nutritional status of LAGB-applied patients should be monitored and mineral supplementation may be considered. © 2011 Springer Science+Business Media, LLC.