ERCIYES MEDICAL JOURNAL, cilt.44, sa.3, ss.347-349, 2022 (ESCI)
Background: Severe acute respiratory syndrome-coronavirus (SARS-CoV) and SARS-CoV-2 might affect the hypothalamic-pituitary-adrenal axis. This paper presents a rare case of pituitary insufficiency diagnosed after CoV disease (COVID)-19.
Case Report: On December 7, 2020, a 67-year-old male patient presented to the Endocrinology Department of Lokman
Hekim University with weakness, weight loss, and abdominal pain lasting for 3 weeks. In his medical history, he had a
positive real-time polymerase chain reaction test result for SARS-CoV-2 based on the nasopharyngeal swab analyzed on
September 30. Central hypothyroidism, secondary adrenal insufficiency, hypogonadotropic hypogonadism, and a low dehydroepiandrosterone-sulfate level were detected in the laboratory examinations. Steroid therapy was initiated.
Conclusion: Non-specific adrenal insufficiency symptoms such as fatigue and weakness, and psychosomatic symptoms can
be seen during the course of COVID-19 or the post-COVID-19 period. Physicians should be aware about the systemic effects
of SARS-CoV-2 infection and follow-up patients with a history of COVID-19 accordingly