Iloprost added to the cardioplegic solutions improves myocardial performance

Katircioglu S., Saritas Z., Ulus A., Yamak B., Yucel D., Ayaz S.

PROSTAGLANDINS & OTHER LIPID MEDIATORS, vol.55, no.1, pp.51-65, 1998 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 1
  • Publication Date: 1998
  • Doi Number: 10.1016/s0090-6980(98)00006-9
  • Journal Name: PROSTAGLANDINS & OTHER LIPID MEDIATORS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.51-65
  • Keywords: iloprost, myocardial performance, ischemia-reperfusion injury, CORONARY-ARTERY OCCLUSION, SPINAL-CORD PROTECTION, REPERFUSION INJURY, ISCHEMIC MYOCARDIUM, NEUTROPHIL ADHESION, RAT-HEART, PROSTACYCLIN, DAMAGE, ENDOTHELIUM, PRESERVATION
  • Lokman Hekim University Affiliated: No

Abstract

A total of 12 mongrel dogs were divided into two equal groups. Six animals received Iloprost and the other 6 animals did not receive any additional treatment. In the Iloprost group, Iloprost was added to the cardioplegic solution (25 ng). Also, Iloprost was used (10 ng/kg/min.) 5 min. before and after cross-clamping.