Treasure from garden: chemical profiling, pharmacology and biotechnology of mulleins

Alipieva K. I., ERDOĞAN ORHAN İ., ÇANKAYA İ. İ., Kostadinova E. P., Georgiev M. I.

PHYTOCHEMISTRY REVIEWS, cilt.13, sa.2, ss.417-444, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 13 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s11101-014-9361-5
  • Dergi Adı: PHYTOCHEMISTRY REVIEWS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.417-444
  • Anahtar Kelimeler: Verbascum, Iridoids, Phenylethanoids, Metabolomics, Anti-inflammatory, Hairy roots, MACROCYCLIC SPERMINE ALKALOIDS, ACYLATED IRIDOID GLYCOSIDES, VERBASCUM PSEUDONOBILE STOJ, PHENYLETHANOID GLYCOSIDES, ANTIINFLAMMATORY PROPERTIES, ANTIMICROBIAL ACTIVITY, ANTIOXIDANT ACTIVITIES, STRUCTURE ELUCIDATION, TRITERPENE SAPONINS, METHANOLIC EXTRACT
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

The genus Verbascum (mulleins), belonging to the family Scrophulariaceae, comprises about 360 species of flowering plants. The leaves, flowers and whole aerial parts of Verbascum spp. have been widely used in traditional medicine for the treatment of respiratory and inflammatory disorders and also display powerful wound healing activity. Verbascum species are found to accumulate several groups of bioactive molecules, therefore they might be utilized as attractive sources of new (drug) leads. The present review attempts to provide an up-to-date comprehensive overview on phytochemical and pharmacological aspects of Verbacum spp. research along with some successful examples of growing (and transforming) mulleins in vitro.