INVESTIGATION OF THE ACTN3 GENE POLYMORPHISM (RS1815739) AND FMS VALUES IN YOUNG RUNNERS: CROSS-SECTIONAL RESEARCH


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Bulğay C., Bayraktar I., Ödemiş M., Yıldırım D. S., Ergün M. A., Cerit M., ...More

JOURNAL OF SPORTS SCIENCES, pp.1-7, 2023 (SCI-Expanded)

  • Publication Type: Article / Article
  • Publication Date: 2023
  • Doi Number: 10.5336/sportsci.2022-94239
  • Journal Name: JOURNAL OF SPORTS SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, IBZ Online, BIOSIS, CAB Abstracts, CINAHL, Educational research abstracts (ERA), Food Science & Technology Abstracts, MEDLINE, SportDiscus
  • Page Numbers: pp.1-7
  • Lokman Hekim University Affiliated: Yes

Abstract

The present study aims to examine investi- gation the -actinin-3 (ACTN3) gene polymorphism (rs1815739) and functional movement screen (FMS) values in young runners competing at the national level. Material and Methods: Forty-five young runners (29 male 64.4%, 16 female 35.6%) competing at the national level in different clubs affiliated to the Turkish Athletic Federation and training regularly at least 5 days a week voluntarily participated in the study. The DNA isolation of oral swab samples was carried out using the spin column (MN Macherey-Nagel, Germany) method. The genotyping pro- cess was performed using the real-time polymerase chain reaction method. Results: The FMS test battery was used to determine the func- tional capacity. According to the findings obtained, it was determined that in the FMS evaluation of the female runners, the runners with the CC genotype had a significantly higher mean score compared to the runners with the CT genotype (p<0.033) while in the male runners, the runners with the CT genotype had a significantly higher mean score compared to the runners with the TT genotype (p<0.031). However, in the FMS evaluation of the overall runners, no significant difference was found (p>0.205). Conclusion: It is thought that the FMS test battery and the ACTN3 gene polymorphism, which is among the important variables responsible for non-impact injuries, can be effective in the level of muscle damage, the type of muscle injury, the prediction of in- juries and reducing the risk factors that may cause injuries.