Synthesis and antimicrobial activity of some new 4-hydroxy-2H-1,4-benzoxazin-3(4H)-ones

ÖZDEN M. S., Öztürk A. M., GÖKER A. H., ALTANLAR N.

Farmaco, vol.55, no.11-12, pp.715-718, 2000 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 11-12
  • Publication Date: 2000
  • Doi Number: 10.1016/s0014-827x(00)00098-7
  • Journal Name: Farmaco
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.715-718
  • Keywords: 4-hydroxy-2H-1,4-benzoxazin-3(4H)-one, antibacterial and antifungal activity, HYDROXAMIC ACID CONTENT, DERIVATIVES, GRAMINEAE, PLANTS, WHEAT
  • Lokman Hekim University Affiliated: No

Abstract

Some 4-hydroxy-2H-1,4-benzoxazin-3(4H)-ones were synthesized and evaluated for their antimicrobial activities against Staphylococcus aureus, Escherichia coli and Candida albicans. Compounds 9, and 10 exhibited the best activity against Candida albicans. Copyright © 2000 Elsevier Science S.A.