Catheter-directed thrombolysis of acute lower extremity arterial thrombosis in a patient with heparin-induced thrombocytopenia

Turba U. C., Bozlar U., ŞİMŞEK S.

Catheterization and Cardiovascular Interventions, cilt.70, sa.7, ss.1046-1050, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 70 Sayı: 7
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1002/ccd.21304
  • Dergi Adı: Catheterization and Cardiovascular Interventions
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1046-1050
  • Anahtar Kelimeler: heparin-induced thrombocytopenia, thrombolysis, t-PA, argatroban, COMPLICATIONS, THERAPY
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Heparin-induced thrombocytopenia (HIT) is an underdiagnosed problem, and the optimal treatment of arterial thrombosis in patients with HIT remains controversial. There are many angiographic procedures which require heparin as an adjunctive agent; however, some of the heparin-related complications and their management remains unclear. We are presenting a 77-year-old male patient with HIT, who developed acute lower extremity limb threatening ischemia due to arterial thrombosis. In our case, the patient has been successfully treated with percutaneous catheterdirected thrombolysis with tissue plasminogen activator and a direct thrombin inhibitor argatroban. © 2007 Wiley-Liss. Inc.