Protection of farm goats by combinations of recombinant peptides and formalin inactivated spores from a lethal Bacillus anthracis challenge under field conditions

Koehler, Susanne; Buyuk, Fatih; Celebi, Ozgur; Demiraslan, Hayati; DOĞANAY, MEHMET; Sahin, Mitat; Moehring, Jens; Ndumnego, Okechukwu; Otlu, Salih; van Heerden, Henriette; Beyer, Wolfgang

doi:10.1186/s12917-017-1140-2

Protection of farm goats by combinations of recombinant peptides and formalin inactivated spores from a lethal Bacillus anthracis challenge under field conditions

Koehler S. M., Buyuk F., Celebi O., Demiraslan H., DOĞANAY M., Sahin M., ...Daha Fazla

BMC VETERINARY RESEARCH, cilt.13, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 13
Basım Tarihi: 2017
Doi Numarası: 10.1186/s12917-017-1140-2
Dergi Adı: BMC VETERINARY RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: Bacillus anthracis, Anthrax, Vaccination, Animal vaccine, COMPARATIVE EFFICACY, SUBOPTIMAL AMOUNTS, GUINEA-PIGS, VACCINE, ANTIGEN, MICE, IMMUNIZATION, PROTEIN, STRAINS, TOXIN
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Background: Bacillus (B.) anthracis, the causal agent of anthrax, is effectively controlled by the Sterne live spore vaccine (34F2) in animals. However, live spore vaccines are not suitable for simultaneous vaccination and antibiotic treatment of animals being at risk of infection in an outbreak situation. Non-living vaccines could close this gap.