Protection of farm goats by combinations of recombinant peptides and formalin inactivated spores from a lethal Bacillus anthracis challenge under field conditions

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Koehler S. M., Buyuk F., Celebi O., Demiraslan H., DOĞANAY M., Sahin M., ...Daha Fazla

BMC VETERINARY RESEARCH, cilt.13, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1186/s12917-017-1140-2
  • Dergi Adı: BMC VETERINARY RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Bacillus anthracis, Anthrax, Vaccination, Animal vaccine, COMPARATIVE EFFICACY, SUBOPTIMAL AMOUNTS, GUINEA-PIGS, VACCINE, ANTIGEN, MICE, IMMUNIZATION, PROTEIN, STRAINS, TOXIN
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Background: Bacillus (B.) anthracis, the causal agent of anthrax, is effectively controlled by the Sterne live spore vaccine (34F2) in animals. However, live spore vaccines are not suitable for simultaneous vaccination and antibiotic treatment of animals being at risk of infection in an outbreak situation. Non-living vaccines could close this gap.