Refractive error may influence mesopic pupil size

Cakmak H. B., ÇAĞIL N., Simavli H., Duzen B., Simsek S.

Current Eye Research, vol.35, no.2, pp.130-136, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 2
  • Publication Date: 2010
  • Doi Number: 10.3109/02713680903447892
  • Journal Name: Current Eye Research
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.130-136
  • Keywords: Mesopic pupil size, Pupilla, Refractive error, Wavefront aberrometer, With the rule astigmatism, VISUAL FUNCTION, VISION, PUPILLOMETER, DIAMETER, QUALITY, MYOPES, LASIK
  • Lokman Hekim University Affiliated: No


Purpose: To identify factors which affect mesopic pupil diameter in refractive surgery patients. Setting: This retrospective study was performed at the 1st Ophthalmology Clinic in Ankara Ataturk Training and Research Hospital, Ankara, Turkey. Methods: Medical records of 412 refractive surgery candidates who applied between 2006 and 2008 were reviewed. Detailed ophthalmological examination data were obtained from medical records. Pupil size measurements were performed with a COAS Ocular Wavefront analyzer in mesopic conditions. Relationship between mesopic pupil diameter and age, sex, spherical refractive error (D), magnitude of astigmatism (D), type of astigmatism, spherical equivalent, and average keratometry were analyzed by means of univariate and multivariate regression analyses. Results: Mean mesopic pupil diameter was 6.19±0.88mm. Mean pupil diameter (mean ± standard deviation) was 5.70±1.01 in hypermetropia, 6.04±0.79mm in mixed astigmatism, and 6.33±0.82mm in myopia. The difference in mean mesopic pupil diameters between myopes and hypermetropes was statistically significant (p0.001). However, differences with regard to mean pupil diameters between myopes and mixed astigmatism (p0.660) and between hypermetropes and mixed astigmatism (p0.109) were not significant. Mean pupil diameter was 6.00±0.99mm in against the rule astigmatism, 5.96±0.84mm in oblique astigmatism, and 6.27±0.84mm in with the rule astigmatism. Mean mesopic pupil diameter in with the rule astigmatism group was higher than oblique astigmatism group. Spherical refractive error (r-0.213, p0.001), cylindrical refractive error (0.197, p0.001), and age (r-0.341, p0.001) showed correlation with pupil diameter. Conclusions: This study showed that age and magnitude of both spherical and cylindrical refractive error are the most determinative factors on mesopic pupil size. © 2010 Informa Healthcare USA, Inc.