Antimicrobial activities of some tetrahydronaphthalene-benzimidazole derivatives

ALAGÖZ Z., YILDIZ S., Buyukbingol E.

Chemotherapy, cilt.53, sa.2, ss.110-113, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 2
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1159/000100011
  • Dergi Adı: Chemotherapy
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.110-113
  • Anahtar Kelimeler: benzimidazoles, antimicrobial agents, retinoids, RETINOIDS
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Novel retinoid derivatives containing a benzimidazole moiety were synthesized and tested for their antimicrobial activity. Their antimicrobial activities against methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis, Candida krusei and Candida albicans were evaluated. While some of the compounds exhibited moderate activity against MRSA, S. aureus, E. faecalis, C. krusei and C. albicans, none of the compounds showed activity against E. coli and P. aeruginosa. Copyright © 2007 S. Karger AG.